- Taking the initiative to get your blood tested is a great way to proactively improve your health. Here’s how.
- The shockingly large gap in conventional cardiac medicine and how to close it right now.
When most men think of hormones, testosterone comes to mind. But, did you know that estrogen is also of critical importance to men?
Published data show that when estrogen levels are unbalanced, the risk of degenerative disease in aging men skyrockets. The non-profit Life Extension Foundation, for example, reported more than 14 years ago that excess estrogen contributes to the development of atherosclerosis. Human studies conducted more than a decade later confirmed this.
In fact, men with even slightly elevated estrogen levels doubled their risk of stroke and had far higher incidences of coronary artery disease. Men with benign prostate enlargement or prostate cancer had higher blood estrogen levels (and often low free testosterone blood levels).
On the other hand, insufficient estrogen predisposes men to osteoporosis and bone fracture.
Importance of Estrogen Balance in Men
Is Verified by the AMA
A study published in the Journal of the American Medical Association measured blood estradiol (a dominant estrogen) in 501 men with chronic heart failure. Compared to men in the middle (or balanced) estrogen quintile, men in the lowest estradiol quintile were 317% more likely to die before a 3-year follow-up – while men in the highest estradiol quintile were 133% more likely to die.
The men in the balanced quintile – with the fewest deaths – had serum estradiol levels between 21.80 and 30.11 pg/mL. This is virtually the ideal range long recommended for men.
The men in the highest quintile who suffered 133% increased death rates had serum estradiol levels of 37.40 pg/mL or above. The lowest estradiol group that suffered a 317% increased death rate had serum estradiol levels under 12.90 pg/mL.
The dramatic increase in mortality in men with unbalanced estrogen (i.e., estradiol levels either too high or too low) is nothing short of astounding. It uncovers a gaping hole in conventional cardiology practice that is easily correctable.
This study revealing the lethal dangers of estrogen imbalance is a compelling reason for men to ensure that they maintain their serum estradiol levels in optimal ranges.
Low Estradiol and Testosterone
Predict Mortality in Aging Men
Sales of testosterone replacement drugs have surged more than 20-fold in response to studies linking low testosterone to a host of common maladies.
In a recent study of 3,014 men aged 69–80 years, serum levels of testosterone and estradiol were measured during a mean follow-up time of 4.5 years. Men with low testosterone had 65% greater all-cause mortality while men with low estradiol suffered 54% more deaths. Those men low in estradiol and testosterone were almost twice as likely to die (a 96% increase in mortality) compared to men in the optimal ranges.
This large study of aged men corroborates prior published reports linking imbalances of testosterone and/or estradiol with greater incidences of degenerative disease and death.
How Do Men Naturally
Make the Estrogen They Need?
Women synthesize most of their estrogen in their ovaries and other reproductive tissues. Men, on the other hand, produce estrogen through a process involving an enzyme called aromatase that transforms testosterone into estradiol.
Aging men sometimes have too much aromatase activity, which causes their testosterone to convert to excess estradiol. This results in depletion of vital testosterone while spiking estradiol to unsafe ranges.
Some men lack aromatase and suffer an estrogen deficit. Other men produce so little endogenous testosterone that there is not enough to convert into estrogen, which causes low levels of both free testosterone and estradiol.
“Free testosterone” is the unbound form that is biologically available to cell receptor sites throughout the body. Measuring free testosterone blood levels is the most accurate way of assessing testosterone status in aging men.
Most testosterone in a man’s body emanates from the testes. Aging results in a decline in testicular output, thus necessitating the topical application of a testosterone cream to restore this vital hormone to youthful levels. Ideal free serum testosterone levels for most aging men are between 20–25 pg/mL.
Testing and Monitoring Your Blood
Could Dramatically Extend Your Life
When looking at the high mortality rates associated with imbalances of these critical hormones, it becomes apparent that a significant number of heart attacks, strokes, bone fractures, and other degenerative diseases are easily preventable.
An all-inclusive blood test panel that includes free testosterone and estradiol can retail for $1,000 at commercial labs.
If your blood test results reveal an imbalance of free testosterone and/or estradiol, you are in a position to initiate immediate corrective action.
Not only can restoring youthful hormone balance save your life, but men (and women) often experience an enhancement in their quality of life after their hormones are adjusted to more optimal ranges.